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GPILS
 
Karen Anderson, M.D.
Assistant Professor

Departments of Psychiatry and Neurology
School of Medicine

410-328-7809


Research

Behavioral symptoms in patients with movement disorders (Huntington's disease, Parkinson's disease); Deep brain stimulation therapy for movement disorders brain imaging; Clinical trials for neurological symptoms of Huntington's disease; Clinical trials for behavioral symptoms in movement disorders.
 


Lab Techniques

  • fMRI
  • Deep brain stimulation

Publications

Selected Publications
  1. Louis ED, Anderson KE, Moskowitz C, et al. Dystonia-predominant adult-onset Huntington disease: association between motor phenotype and age of onset in adults. Arch Neurol 2000; 57(9):1326-1330.
  2. Stern Y, Moeller JR, Anderson KE, Luber B, Zubin NR, DiMauro AA et al. Different brain networks mediate task performance in normal aging and AD: defining compensation. Neurology 2000; 55(9):1291-1297.
  3. Khokhar S, Stern Y, Bell K, Anderson K, et al. Persistent mobility deficit in the absence of deficits in activities of daily living: A risk factor for mortality. J American Geriatric Assoc 49:1539-1543, 2001.
  4. Anderson KE, Perera GM, Hilton J, Zubin N, Dela PR, Stern Y. Functional magnetic resonance imaging study of word recognition in normal elders. Prog Neuropsychopharmacol Biol Psychiatry 2002; 26(4):647-650.
  5. Anderson KE, Louis ED, Stern Y, Marder KS. Cognitive correlates of obsessive and compulsive symptoms in Huntington's disease. Am J Psychiatry 2001; 158(5):799-801
  6. Scarmeas N, Zarahn E, Anderson KE, et al. Association of life activities with cerebral blood flow in Alzheimer disease: implications for the cognitive reserve hypothesis. Arch Neurol 2003; 60(3):359-365.
  7. Scarmeas N. Habeck CG. Stern Y. Anderson KE. APOE genotype and cerebral blood flow in healthy young individuals. JAMA 2003; 290(12):1581-2
  8. Scarmeas N. Zarahn E. Anderson KE. Hilton J. Flynn J. Van Heertum RL. Sackeim HA. Stern Y. Cognitive reserve modulates functional brain responses during memory tasks: a PET study in healthy young and elderly subjects. Neuroimage 2003; 19(3):1215-27
  9. Anderson KE, Lynch K, Zarahn E,et al. H215O PET study of impairment of nonverbal recognition with normal aging. J Neuropsychiatry Clin Neurosci 2005; 17(2):192-200.
  10. Devi G, Williamson J, Massoud F, Anderson K, et al. A comparison of family history of psychiatric disorders among patients with early- and late-onset Alzheimer's disease. J Neuropsych Clin Neurosci. 2004;16(1):57-62.
  11. Scarmeas N, Habeck CG, Hilton J, Anderson KE, Flynn J, Park A, Stern Y. APOE related alterations in cerebral activation even at college age. J Neurol Neurosurg Psychiatry. 2005;76(10):1440-4.
  12. Stern Y, Habeck C, Moeller J, Scarmeas N, Anderson KE, Hilton HJ et al. Brain networks associated with cognitive reserve in healthy young and old adults. Cereb Cortex 2005; 15(4):394-402.
  13. Chatterjee A, Anderson KE, Moskowitz CB, Hauser WA, Marder KS. A comparison of self-report and caregiver assessment of depression, apathy, and irritability in Huntington's disease. J Neuropsychiatry Clin Neurosci. 2005;17(3):378-83.
  14. Scarmeas N, Anderson KE, Hilton J, Park A, Habeck C, Flynn J et al. APOE-dependent PET patterns of brain activation in Alzheimer disease. Neurology 2004; 63(5):913-915.
  15. Scarmeas N, Habeck CG, Hilton J, Anderson KE, Flynn J, Park A et al. APOE related alterations in cerebral activation even at college age. J Neurol Neurosurg Psychiatry 2005; 76(10):1440-1444.
  16. Miyasaki JM, Shannon K, Voon V, Ravina B, Kleiner-Fisman G, Anderson K ,et al. American Academy of Neurology Practice Parameter Guidelines. Treatment of nonmotor symptoms in Parkinson's disease. Neurology. 2006, 11;66(7):996-1002.
  17. Haines S, Chen H, Anderson KE, Fishman PS, Shulman LM, Weiner WJ, Reich SG. When do patients with Parkinson disease disclose their diagnosis? Neurology. 2006;67(3):488-90.
  18. Shulman LM, Pretzer-Aboff I, Anderson KE, Stevenson R, Vaughan CG, Gruber-Baldini AL, Reich SG, Weiner WJ. Related Articles, Links, Subjective report versus objective measurement of activities of daily living in Parkinson's disease. Mov Disord. 2006;21(6):794-9.
  19. Beglinger LJ, Langbehn DR, Duff K, Stierman L, Black DW, Nehl C, Anderson K, et al. Probability of Obsessive and Compulsive Symptoms in Huntington's Disease. Biol Psychiatry. 2007;61(3):415-8
  20. Anderson KE, Gruber-Baldini AL, Vaughan CG, et al. Impact of Psychogenic Movement Disorders versus Parkinson's on Disability, Quality of Life and Psychopathology. In Press, Movement Disorders.
  21. Anderson KE, Lynch K, Marder K, et al. Nonverbal memory in Alzheimers disease: O-15 PET study. In Press, Neurology.
  22. Karen E. Anderson Ann L. Gruber-Baldini, Christopher G. Vaughan, Stephen G. Reich, Paul S. Fishman, William J. Weiner, Lisa M. Shulman. Impact of Psychogenic Movement Disorders versus Parkinson's on Disability, Quality of Life and Psychopathology. In Press, Movement Disorders.

Case Series

  1. Silver J, Anderson, KE. Vasopressin Treats the Persistent Feeling of Coldness after Brain Injury. J. Neuropsychiatry and Clinical Neurosciences, Vol.11:248 252, 1999
  2. Silver J, Rattock J, Anderson KE, "Posttraumatic Stress Disorder and Traumatic Brain Injury". Neurocase Vol. 3, pp. 151 157, 1997

Selected Abstracts

  1. Anderson KE, Vaughan C, Shulman LM, Quality of Life and Mental Health in Parkinson's Disease, Annual Meeting of the American Neuropsychiatry Association, J Neuropsych Clin Neurosci, 16(2):223, 2004.
  2. Malecki EA, Vaughan CG, Anderson KE, Fishman PS, Reich SG, Weiner WJ and Shulman LM, What Symptoms are Most Troubling to Patients with Parkinson's Disease, Neurology, 2004, 62(Suppl 5): A50.
  3. Shulman LM, Anderson KE, Vaughan CG, et al. The Impact of Symptoms of Advanced Parkinson's Disease on Daily Function and Quality of Life, Neurology, 2004, 62(Suppl 5): A335.
  4. Haines S, Chen H, Anderson KE, Fishman PS, Shulman LM, Weiner WJ, Reich SG, Disclosing the Diagnosis of Parkinson's Disease, Patient Experiences, Movement Disorders 2004;19:1126-1127.
  5. Shulman LM, Stevenson R, Anderson KE, Vaughan CG, Gruber-Baldini A, Reich SG, Weiner WJ, Subjective Patient-Report versus Objective Performance-Based Measurement of Activities of Daily Living in Parkinson's Disease, Annals of Neurology 2004;56 (Suppl 8):554.
  6. Anderson KE, Paulsen JS. Effects of Obsessive and Compulsive Symptoms in Huntington's Disease. Journal of Neuropsychiatry and Clinical Neurosciences, 16(2): 224, 2004.
  7. Anderson KE, Mullins R, Holcomb H, Reich S, Fishman P, Weiner WJ, Shulman LM. Executive Function Deficits in Parkinson's Disease: fMRI Study of Planning Ability. J Neuropsychiatry Clin Neurosci 2006;18 (2):254. Presented in poster form at the 2006 American Neuropsychiatric Association meeting, San Diego.

Review Articles

  1. Karen E. Anderson, William J. Weiner. Psychiatric Symptoms in Parkinsonâ?Ts Disease. Current Neurology and Neuroscience Reports, 2002, 2:303-309.
  2. Karen E. Anderson, Jake Mullins. Behavioral Changes Associated with Deep Brain Stimulation Surgery for Parkinson's Disease. Current Neurology and Neuroscience Reports 2003, 3:306-313.
  3. Karen E. Anderson, Karen S. Marder. An Overview of Psychiatric Symptoms in Huntington's Disease. Current Psychiatry Reports 2001, 3:379-388.
  4. Karen E. Anderson. Psychogenic Movement Disorders. Current Treatment Options in Neurology 2003, 5:169-176.
  5. Anderson KE, Savage CR. Cognitive and neurobiological findings in obsessive-compulsive disorder. Psychiatr Clin North Am. 2004 Mar;27(1):37-47, viii.
  6. Anderson KE. Dementia in Parkinson's Disease. Curr Treat Options Neurol. 2004 May;6(3):201-207.
  7. Arciniegas DB, Lauterbach EC, Anderson KE, Chow TW, Flashman LA, Hurley RA, Kaufer DI, McAllister TW, Reeve A, Schiffer RB, Silver JM. The differential diagnosis of pseudobulbar affect (PBA). Distinguishing PBA among disorders of mood and affect. Proceedings of a roundtable meeting.CNS Spectr. 2005 May;10(5):1-14.
  8. Anderson KE. Huntington's disease and related disorders. Psychiatr Clin North Am. 2005 Mar;28(1):275-90.
  9. Anderson KE. Evaluation and diagnosis of psychogenic disorders in neurological patients. Semin Neurol. 2006 Jul;26(3):283-8.
  10. Salter BC, Anderson KE, Weiner WJ. Psychosis in Parkinson's disease: case studies. Neurol Clin. 2006 May;24(2):363-9.

Books

  1. Anderson KE, Weiner WJ, Lang AE (Editors). Behavioral Neurology of Movement Disorders, Second Edition, Advances in Neurology Series, Lippincott, Williams & Wilkins, Philadelphia, 2005.

Editorships of Journals

  1. Current Treatment Options in Neurology - Psychiatry Section Editor, 2006-present

Chapters

  1. Karen Anderson, Jon Silver, "Neurological and Medical Diseases" In: Medical Management of the Violent Patient. Ken Tardiff, Editor, Marcel Decker Press, NY. pp. 87 124, 1999.
  2. Karen E. Anderson, Karen Marder. Huntington's Disease. Current Therapy in Neurologic Disese. 6th Edition. Edited by Richard T. Johnson, John W. Griffin, Justin C. McArthur. Pp282-287.
  3. Karen E. Anderson, Robin Hurley, Katherine Taber. Neuroimaging in Traumatic Brain Injury. American Psychiatric Association Textbook of Traumatic Brain Injury. APA Press. Edited by J. Silver and T. McAllister. 2004.
  4. Karen E. Anderson, Karen S. Marder. Huntington's Disease. Psychiatry for Neurologists, 2005.
  5. Anderson KE, Marshall FJ. Behavioral symptoms associated with Huntington's disease. Adv Neurol. 2005;96:197-208.
  6. Anderson, KE. Treatment of Dementia, In: Parkinson's Disease: Diagnosis and Clinical Management, Second Edition, Edited by Stewart Factor, M.D. and William J. Weiner, M.D., In Press

 

Personal History

Education

  • 1984-1988: Bachelor of Arts, University of Chicago, The College        
  • 1989-1993: Medical Doctor, University of Chicago Pritzker Medical School
  • 1999-2001: Masters in Biostatistics, Columbia University Mailman School of Public Health, Patient Oriented Research Program                 

Post Graduate Education and Training   

  • 1993-94: Medical Intern, Columbia Presbyterian Medical Center
  • 1994-1997: Psychiatry Resident, Columbia University & the New York State Psychiatric Institute
  • 1997-2000: Schizophrenia Research Fellow, Columbia University & the New York State Psychiatric Institute
  • 2006-present: Deep Brain Stimulation Fellowship at University of Maryland Movement Disorders Program, Sponsored by Medtronic, with focus on treatment of Parkinson's and other Movement Disorders

Certifications

  • Psychiatry Diplomate, 1998
  • Neuropsychiatry and Behavioral Neurology Subspecialty Certification, 2006

Medical Licensure

  • Maryland

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